A new season of football is upon us, and our Pro Football Pick 'Em has returned with your chance to win great weekly prizes, as well as an end of season prize that includes your chance to win $10,000.

For your best chance to win the Week 1 prize, you'll want to pick the winner of Thursday's season opener between Philadelphia and Atlanta prior to kickoff at 8:20 p.m.

If you don't select a team for the Thursday night game, you can still finish the week with the high score, as long as you pick teams from the other games prior to their scheduled kickoff times.

This week's prize, flip coins from each of the Patriots' last two trips to the Big Game.

You can play Pick 'Em at any time during the regular season. The player with the highest combined score at the end of the season will win a grand prize that comes with the opportunity to win some serious cash.

The winner will predict the halftime and final scores of the Big Game on Feb. 3. Get one score right, win $1,000. Get them both right and walk away with $10,000.

To make picks throughout the regular season, including Week 1, click here.