David Price pitched six innings of two-run ball, Mookie Betts and David Ortiz hit two-run homers and the Red Sox won their season opener 6-2 over Cleveland.

After Price, Junichi Tazawa, Koji Uehara and Craig Kimbrell all pitched a inning.

Betts , Ortiz, Hanley Ramirez, Travis Shaw and Brock Holt all had two hits.