The third round of the NCAA Tournament features a trio of compelling matchups in the Midwest Region.

Louisville dominated Colorado State in impressive fashion, while Michigan State came off a pummeling of Valparaiso to rout a Memphis squad that held on for dear life against Saint Mary’s. Saint Louis and its stingy defense was upset by an Oregon squad whose victory over Oklahoma State already proved the selection committee was way off base giving it a #12 seed.

All start times are approximate. All times Eastern.

(12) Oregon 74, (4) Saint Louis 57

Damyean Dotson scored 23 points, and 12th-seeded Oregon upset fourth-seeded Saint Louis, 74-57, in a third round game of the 2013 NCAA tournament's Midwest Region in San Jose, Calif. on Saturday. The Ducks jumped out to a big lead in the first half, but Saint Louis whittled the margin down to 11 in the second half before fading. Oregon made eight of 11 three-point shot attempts during the victory. The Ducks advanced and will face top-seeded Louisville in the round of 16 in Indianapolis on Friday. Kwamain Mitchell led the Billikens with 18 points. Saint Louis shot just 3-for-21 from the 3-point line.

(1) Louisville 82, (8) Colorado State 56

Russ Smith scored 27 points, and top-seeded Louisville drilled Colorado State, 82-56, in a third round game of the 2013 NCAA tournament's Midwest Region in Lexington, Ky. on Saturday. The Cardinals forced several turnovers during a pivotal first-half run that gave them a 14-point lead at the half. Smith made four of five 3-point shots during the early onslaught, and the Rams never closed the gap. Louisville advanced to the round of 16 and will face Oregon in Indianapolis next Friday. Greg Smith scored 14 for Colorado State, while teammate Colton Iverson added nine points and seven rebounds.

(3) Michigan State 70, (6) Memphis 48

Gary Harris scored 23 points, and third-seeded Michigan State used a huge second half to rout sixth-seeded Memphis, 70-48, in a third round game of the 2013 NCAA tournament's Midwest Region in Auburn Hills, Mich. on Saturday. Adreian Payne added 14 points and 12 rebounds for the Spartans, who led by just three points at halftime but pulled away thanks to a solid defensive second half. Star guard Keith Appling scored just two points for the Spartans and left due to a shoulder injury with about 7:14 remaining. Michigan State advanced to the round of 16 in Indianapolis next Friday. Memphis shot just 30 percent from the field, including 5-for-23 from 3-point range. Geron Johnson led the Tigers with 16 points.

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